Iso-acoustic focusing of cells for size-insensitive acousto-mechanical phenotyping

Acoustophoresis, a method to manipulate individual cells based on their acoustic properties is confounded by a strong dependency on cell size. Here the authors present iso-acoustic focussing, a way to separate cells in a microfluidic chamber according to their effective acoustic impedance, independe...

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Bibliographic Details
Main Authors: Per Augustsson, Jonas T. Karlsen, Hao-Wei Su, Henrik Bruus, Joel Voldman
Format: Article
Language:English
Published: Nature Portfolio 2016-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11556