Acquisition of bipedal locomotion in a neuromusculoskeletal model with unilateral transtibial amputation
Adaptive locomotion is an essential behavior for animals to survive. The central pattern generator in the spinal cord is responsible for the basic rhythm of locomotion through sensory feedback coordination, resulting in energy-efficient locomotor patterns. Individuals with symmetrical body proportio...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-03-01
|
| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1130353/full |
| _version_ | 1811162625241776128 |
|---|---|
| author | Daisuke Ichimura Hiroaki Hobara Genki Hisano Genki Hisano Genki Hisano Tsubasa Maruyama Mitsunori Tada |
| author_facet | Daisuke Ichimura Hiroaki Hobara Genki Hisano Genki Hisano Genki Hisano Tsubasa Maruyama Mitsunori Tada |
| author_sort | Daisuke Ichimura |
| collection | DOAJ |
| description | Adaptive locomotion is an essential behavior for animals to survive. The central pattern generator in the spinal cord is responsible for the basic rhythm of locomotion through sensory feedback coordination, resulting in energy-efficient locomotor patterns. Individuals with symmetrical body proportions exhibit an energy-efficient symmetrical gait on flat ground. In contrast, individuals with lower limb amputation, who have morphologically asymmetrical body proportions, exhibit asymmetrical gait patterns. However, it remains unclear how the nervous system adjusts the control of the lower limbs. Thus, in this study, we investigated how individuals with unilateral transtibial amputation control their left and right lower limbs during locomotion using a two-dimensional neuromusculoskeletal model. The model included a musculoskeletal model with 7 segments and 18 muscles, as well as a neural model with a central pattern generator and sensory feedback systems. Specifically, we examined whether individuals with unilateral transtibial amputation acquire prosthetic gait through a symmetric or asymmetric feedback control for the left and right lower limbs. After acquiring locomotion, the metabolic costs of transport and the symmetry of the spatiotemporal gait factors were evaluated. Regarding the metabolic costs of transportation, the symmetric control model showed values approximately twice those of the asymmetric control model, whereas both scenarios showed asymmetry of spatiotemporal gait patterns. Our results suggest that individuals with unilateral transtibial amputation can reacquire locomotion by modifying sensory feedback parameters. In particular, the model reacquired reasonable locomotion for activities of daily living by re-searching asymmetric feedback parameters for each lower limb. These results could provide insight into effective gait assessment and rehabilitation methods to reacquire locomotion in individuals with unilateral transtibial amputation. |
| first_indexed | 2024-04-10T06:32:24Z |
| format | Article |
| id | doaj.art-e3bfe719d3f1412981db1dac5c97ea8f |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-04-10T06:32:24Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-e3bfe719d3f1412981db1dac5c97ea8f2023-03-01T05:33:16ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852023-03-011110.3389/fbioe.2023.11303531130353Acquisition of bipedal locomotion in a neuromusculoskeletal model with unilateral transtibial amputationDaisuke Ichimura0Hiroaki Hobara1Genki Hisano2Genki Hisano3Genki Hisano4Tsubasa Maruyama5Mitsunori Tada6Artificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo, JapanFaculty of Advanced Engineering, Tokyo University of Science, Tokyo, JapanArtificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo, JapanDepartment of Systems and Control Engineering, Tokyo Institute of Technology, Tokyo, JapanResearch Fellow of Japan Society for the Promotion of Science (JSPS), Tokyo, JapanArtificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo, JapanArtificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo, JapanAdaptive locomotion is an essential behavior for animals to survive. The central pattern generator in the spinal cord is responsible for the basic rhythm of locomotion through sensory feedback coordination, resulting in energy-efficient locomotor patterns. Individuals with symmetrical body proportions exhibit an energy-efficient symmetrical gait on flat ground. In contrast, individuals with lower limb amputation, who have morphologically asymmetrical body proportions, exhibit asymmetrical gait patterns. However, it remains unclear how the nervous system adjusts the control of the lower limbs. Thus, in this study, we investigated how individuals with unilateral transtibial amputation control their left and right lower limbs during locomotion using a two-dimensional neuromusculoskeletal model. The model included a musculoskeletal model with 7 segments and 18 muscles, as well as a neural model with a central pattern generator and sensory feedback systems. Specifically, we examined whether individuals with unilateral transtibial amputation acquire prosthetic gait through a symmetric or asymmetric feedback control for the left and right lower limbs. After acquiring locomotion, the metabolic costs of transport and the symmetry of the spatiotemporal gait factors were evaluated. Regarding the metabolic costs of transportation, the symmetric control model showed values approximately twice those of the asymmetric control model, whereas both scenarios showed asymmetry of spatiotemporal gait patterns. Our results suggest that individuals with unilateral transtibial amputation can reacquire locomotion by modifying sensory feedback parameters. In particular, the model reacquired reasonable locomotion for activities of daily living by re-searching asymmetric feedback parameters for each lower limb. These results could provide insight into effective gait assessment and rehabilitation methods to reacquire locomotion in individuals with unilateral transtibial amputation.https://www.frontiersin.org/articles/10.3389/fbioe.2023.1130353/fullamputee locomotionneuromusculoskeletal modelcentral pattern generatorsensory feedbackunilateral transtibial amputationpathological locomotion |
| spellingShingle | Daisuke Ichimura Hiroaki Hobara Genki Hisano Genki Hisano Genki Hisano Tsubasa Maruyama Mitsunori Tada Acquisition of bipedal locomotion in a neuromusculoskeletal model with unilateral transtibial amputation Frontiers in Bioengineering and Biotechnology amputee locomotion neuromusculoskeletal model central pattern generator sensory feedback unilateral transtibial amputation pathological locomotion |
| title | Acquisition of bipedal locomotion in a neuromusculoskeletal model with unilateral transtibial amputation |
| title_full | Acquisition of bipedal locomotion in a neuromusculoskeletal model with unilateral transtibial amputation |
| title_fullStr | Acquisition of bipedal locomotion in a neuromusculoskeletal model with unilateral transtibial amputation |
| title_full_unstemmed | Acquisition of bipedal locomotion in a neuromusculoskeletal model with unilateral transtibial amputation |
| title_short | Acquisition of bipedal locomotion in a neuromusculoskeletal model with unilateral transtibial amputation |
| title_sort | acquisition of bipedal locomotion in a neuromusculoskeletal model with unilateral transtibial amputation |
| topic | amputee locomotion neuromusculoskeletal model central pattern generator sensory feedback unilateral transtibial amputation pathological locomotion |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1130353/full |
| work_keys_str_mv | AT daisukeichimura acquisitionofbipedallocomotioninaneuromusculoskeletalmodelwithunilateraltranstibialamputation AT hiroakihobara acquisitionofbipedallocomotioninaneuromusculoskeletalmodelwithunilateraltranstibialamputation AT genkihisano acquisitionofbipedallocomotioninaneuromusculoskeletalmodelwithunilateraltranstibialamputation AT genkihisano acquisitionofbipedallocomotioninaneuromusculoskeletalmodelwithunilateraltranstibialamputation AT genkihisano acquisitionofbipedallocomotioninaneuromusculoskeletalmodelwithunilateraltranstibialamputation AT tsubasamaruyama acquisitionofbipedallocomotioninaneuromusculoskeletalmodelwithunilateraltranstibialamputation AT mitsunoritada acquisitionofbipedallocomotioninaneuromusculoskeletalmodelwithunilateraltranstibialamputation |