Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer’s disease therapy

Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer’s disease therapy

In view of the multifactorial nature of Alzheimer’s disease (AD), multitarget small molecules (MTSM) represent the most potent and attractive therapeutic strategy to design new drugs for Alzheimer’s disease therapy. The new MTSM KojoTacrines (KTs) were designed and synthesized by juxtaposition of se...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Youssef Dgachi, Hélène Martin, Rim Malek, Daniel Jun, Jana Janockova, Vendula Sepsova, Ondrej Soukup, Isabel Iriepa, Ignacio Moraleda, Emna Maalej, M. Carmo Carreiras, Bernard Refouvelet, Fakher Chabchoub, José Marco-Contelles, Lhassane Ismaili
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Taylor & Francis Group 2019-01-01
Цуврал:Journal of Enzyme Inhibition and Medicinal Chemistry
Нөхцлүүд:
alzheimer disease
kojic acid
multitarget small molecules
tacrine
Онлайн хандалт:http://dx.doi.org/10.1080/14756366.2018.1538136

Интернэт

http://dx.doi.org/10.1080/14756366.2018.1538136

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