Microrna-130a Downregulates HCV Replication through an atg5-Dependent Autophagy Pathway

Microrna-130a Downregulates HCV Replication through an atg5-Dependent Autophagy Pathway

We previously identified that miR-130a downregulates HCV replication through two independent pathways: restoration of host immune responses and regulation of pyruvate metabolism. In this study, we further sought to explore host antiviral target genes regulated by miR-130a. We performed a RT&#178...

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Bibliographic Details
Main Authors: Xiaoqiong Duan, Xiao Liu, Wenting Li, Jacinta A. Holmes, Annie J. Kruger, Chunhui Yang, Yujia Li, Min Xu, Haiyan Ye, Shuang Li, Xinzhong Liao, Qiuju Sheng, Dong Chen, Tuo Shao, Zhimeng Cheng, Batul Kaj, Esperance A. Schaefer, Shilin Li, Limin Chen, Wenyu Lin, Raymond T. Chung
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cells
Subjects:
miR-130a
autophagy
autophagy-related genes 5 (ATG5), ATG12
hepatitis C virus (HCV), interferon stimulated gene (ISG)
Online Access:https://www.mdpi.com/2073-4409/8/4/338

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https://www.mdpi.com/2073-4409/8/4/338

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