Sulfonylureas exert antidiabetic action on adipocytes by inhibition of PPARγ serine 273 phosphorylation

Sulfonylureas exert antidiabetic action on adipocytes by inhibition of PPARγ serine 273 phosphorylation

Objective: Sulfonylureas (SUs) are still among the mostly prescribed antidiabetic drugs with an established mode of action: release of insulin from pancreatic β-cells. In addition, effects of SUs on adipocytes by activation of the nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ)...

Full description

Bibliographic Details
Main Authors: Bodo Haas, Moritz David Sebastian Hass, Alexander Voltz, Matthias Vogel, Julia Walther, Arijit Biswas, Daniela Hass, Alexander Pfeifer
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:Molecular Metabolism
Subjects:
Sulfonylureas
PPARγ
White adipose tissue
Brown adipose tissue
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877824000875

Internet

http://www.sciencedirect.com/science/article/pii/S2212877824000875

Similar Items