Macrophage S1PR1 Signaling Alters Angiogenesis and Lymphangiogenesis During Skin Inflammation

Macrophage S1PR1 Signaling Alters Angiogenesis and Lymphangiogenesis During Skin Inflammation

The bioactive lipid sphingosine-1-phosphate (S1P), along with its receptors, modulates lymphocyte trafficking and immune responses to regulate skin inflammation. Macrophages are important in the pathogenesis of psoriasiform skin inflammation and express various S1P receptors. How they respond to S1P...

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Bibliographic Details
Main Authors: Shahzad Nawaz Syed, Rebecca Raue, Andreas Weigert, Andreas von Knethen, Bernhard Brüne
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
macrophage
S1PR1
sphingosine-1-phosphate
psoriasis
inflammation
lymphangiogenesis
angiogenesis
Online Access:https://www.mdpi.com/2073-4409/8/8/785

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https://www.mdpi.com/2073-4409/8/8/785

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