Dynamic increase in extracellular ATP accelerates photoreceptor cell apoptosis via ligation of P2RX7 in subretinal hemorrhage.

Dynamic increase in extracellular ATP accelerates photoreceptor cell apoptosis via ligation of P2RX7 in subretinal hemorrhage.

Photoreceptor degeneration is the most critical cause of visual impairment in age-related macular degeneration (AMD). In neovascular form of AMD, severe photoreceptor loss develops with subretinal hemorrhage due to choroidal neovascularization (CNV), growth of abnormal blood vessels from choroidal c...

Full description

Bibliographic Details
Main Authors: Shoji Notomi, Toshio Hisatomi, Yusuke Murakami, Hiroto Terasaki, Shozo Sonoda, Ryo Asato, Atsunobu Takeda, Yasuhiro Ikeda, Hiroshi Enaida, Taiji Sakamoto, Tatsuro Ishibashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3540091?pdf=render

Internet

http://europepmc.org/articles/PMC3540091?pdf=render

Similar Items