Ganoderma spore lipid ameliorates docetaxel, cisplatin, and 5-fluorouracil chemotherapy-induced damage to bone marrow mesenchymal stem cells and hematopoiesis

Ganoderma spore lipid ameliorates docetaxel, cisplatin, and 5-fluorouracil chemotherapy-induced damage to bone marrow mesenchymal stem cells and hematopoiesis

Abstract Background A triplet chemotherapy regimen of docetaxel, cisplatin, and 5-fluorouracil (TPF) is used to treat head and neck squamous cell carcinoma; however, it is toxic to bone marrow mesenchymal stem cells (BMSCs). We previously demonstrated that Ganoderma spore lipid (GSL) protect BMSCs a...

Full description

Bibliographic Details
Main Authors: Haohui Lin, Manhon Chung, Jingchun Sun, Yi Yang, Li Zhang, Xiaohua Pan, Minghui Wei, Sa Cai, Yu Pan
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Head and neck squamous cell carcinoma
Chemotherapy
Docetaxel, cisplatin, and 5-fluorouracil
Ganoderma spore lipid
Bone marrow mesenchymal stem cell
Hematopoiesis
Online Access:https://doi.org/10.1186/s12906-024-04445-x

Internet

https://doi.org/10.1186/s12906-024-04445-x

Similar Items