A Ferritin Nanoparticle-Based Zika Virus Vaccine Candidate Induces Robust Humoral and Cellular Immune Responses and Protects Mice from Lethal Virus Challenge

A Ferritin Nanoparticle-Based Zika Virus Vaccine Candidate Induces Robust Humoral and Cellular Immune Responses and Protects Mice from Lethal Virus Challenge

The severe consequences of the Zika virus (ZIKV) infections resulting in congenital Zika syndrome in infants and the autoimmune Guillain–Barre syndrome in adults warrant the development of safe and efficacious vaccines and therapeutics. Currently, there are no approved treatment options for ZIKV inf...

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Bibliographic Details
Main Authors: Aryamav Pattnaik, Bikash R. Sahoo, Lucas R. Struble, Gloria E. O. Borgstahl, You Zhou, Rodrigo Franco, Raul G. Barletta, Fernando A. Osorio, Thomas M. Petro, Asit K. Pattnaik
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Vaccines
Subjects:
Zika virus
envelope protein domain III
ferritin
nanoparticles
neutralizing antibody response
cell-mediated response
Online Access:https://www.mdpi.com/2076-393X/11/4/821

Internet

https://www.mdpi.com/2076-393X/11/4/821

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