A Desmethylphosphinothricin Dipeptide Derivative Effectively Inhibits <i>Escherichia coli</i> and <i>Bacillus subtilis</i> Growth

A Desmethylphosphinothricin Dipeptide Derivative Effectively Inhibits <i>Escherichia coli</i> and <i>Bacillus subtilis</i> Growth

New antibiotics are unquestionably needed to fight the emergence and spread of multidrug-resistant bacteria. To date, antibiotics targeting bacterial central metabolism have been poorly investigated. By determining the minimal inhibitory concentration (MIC) of desmethylphosphinothricin (Glu-γ-P<s...

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Bibliographic Details
Main Authors: Maxim A. Khomutov, Fabio Giovannercole, Laura Onillon, Marija V. Demiankova, Byazilya F. Vasilieva, Arthur I. Salikhov, Sergey N. Kochetkov, Olga V. Efremenkova, Alex R. Khomutov, Daniela De Biase
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomolecules
Subjects:
antibacterial
glutamate metabolism
antimicrobial resistance
central metabolism
dipeptide permeases
phosphorus-containing glutamate analogues
Online Access:https://www.mdpi.com/2218-273X/13/10/1451

Internet

https://www.mdpi.com/2218-273X/13/10/1451

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