Application of ultrasound accelerates the decalcification process of bone matrix without affecting histological and immunohistochemical analysis
Background/Objectives: Decalcification of bone specimens is necessary for routine paraffin embedding and sectioning. Ethylenediaminetetraacetic acid (EDTA), a chelating agent for decalcification, maintains bone tissue integrity and histological features but requires long decalcification period, espe...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-04-01
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| Series: | Journal of Orthopaedic Translation |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214031X18300962 |