A Hearty Dose of Noncoding RNAs: The Imprinted DLK1-DIO3 Locus in Cardiac Development and Disease

A Hearty Dose of Noncoding RNAs: The Imprinted DLK1-DIO3 Locus in Cardiac Development and Disease

The imprinted Dlk1-Dio3 genomic region harbors a noncoding RNA cluster encoding over fifty microRNAs (miRNAs), three long noncoding RNAs (lncRNAs), and a small nucleolar RNA (snoRNA) gene array. These distinct noncoding RNAs (ncRNAs) are thought to arise from a single polycistronic transcript that i...

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Bibliographic Details
Main Authors: Tiffany L. Dill, Francisco J. Naya
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
cardiac
proliferation
hypertrophy
fibrosis
microRNA
long noncoding RNA
imprinting
epigenetics
Online Access:http://www.mdpi.com/2308-3425/5/3/37

Internet

http://www.mdpi.com/2308-3425/5/3/37

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