Profiling the peripheral blood T cell receptor repertoires of gastric cancer patients

Profiling the peripheral blood T cell receptor repertoires of gastric cancer patients

Cancer driven by somatic mutations may express neoantigens that can trigger T-cell immune responses. Since T-cell receptor (TCR) repertoires play critical roles in anti-tumor immune responses for oncology, next-generation sequencing (NGS) was used to profile the hypervariable complementarity-determi...

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Bibliographic Details
Main Authors: Mengyao Wang, Peng Gao, Laifeng Ren, Jingjing Duan, Silu Yang, Haina Wang, Hongxia Wang, Junning Sun, Xiaoyan Gao, Bo Li, Shuaicheng Li, Wen Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
TCR repertoire
next-generation sequencing
gastric cancer
biomarker
antitumor immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.848113/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.848113/full

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