Discovery of β‐nitrostyrene derivatives as potential quorum sensing inhibitors for biofilm inhibition and antivirulence factor therapeutics against Serratia marcescens

Discovery of β‐nitrostyrene derivatives as potential quorum sensing inhibitors for biofilm inhibition and antivirulence factor therapeutics against Serratia marcescens

Abstract Quorum sensing (QS) inhibition has emerged as a promising target for directed drug design, providing an appealing strategy for developing antimicrobials, particularly against infections caused by drug‐resistant pathogens. In this study, we designed and synthesized a total of 33 β‐nitrostyre...

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Bibliographic Details
Main Authors: Jiang Wang, Jingyi Yang, Pradeepraj Durairaj, Wei Wang, Dongyan Wei, Shi Tang, Haiqing Liu, Dayong Wang, Ai‐Qun Jia
Format: Article
Language:English
Published: Wiley 2024-09-01
Series:mLife
Subjects:
biofilms
quorum sensing
Serratia marcescens
virulence factors
(E)‐1‐methyl‐4‐(2‐nitrovinyl)benzene
Online Access:https://doi.org/10.1002/mlf2.12135

Internet

https://doi.org/10.1002/mlf2.12135

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