Improvement of early developmental competence of postovulatory‐aged oocytes using metaphase II spindle injection in mice

Abstract Purpose Assisted reproductive technology (ART) is a widely applied fertility treatment. However, the developmental competence of aged oocytes from women of a late reproductive age is seriously reduced and the aged oocytes often fail in fertilization even when ART is used. To resolve this pr...

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Bibliographic Details
Main Authors: Tatsuyuki Ogawa, Hiroko Fukasawa, Shuji Hirata
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Reproductive Medicine and Biology
Subjects:
Online Access:https://doi.org/10.1002/rmb2.12335