Phosphodiester models for cleavage of nucleic acids

Nucleic acids that store and transfer biological information are polymeric diesters of phosphoric acid. Cleavage of the phosphodiester linkages by protein enzymes, nucleases, is one of the underlying biological processes. The remarkable catalytic efficiency of nucleases, together with the ability of...

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Bibliographic Details
Main Authors: Satu Mikkola, Tuomas Lönnberg, Harri Lönnberg
Format: Article
Language:English
Published: Beilstein-Institut 2018-04-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.14.68