First Direct Isolation of Stable α-Form Crystals of Mirabegron, a Selective β3–Adrenoceptor Agonist

First Direct Isolation of Stable α-Form Crystals of Mirabegron, a Selective β3–Adrenoceptor Agonist

An efficient and scalable method for the direct isolation of stable α-form crystals of mirabegron (1) is developed. The developed method negates transformation of metastable β-form crystals into α-form crystals thereby overcome the limitations of reported methods and avoids additional processing ste...

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Bibliographic Details
Main Authors: Vijayavitthal T. Mathad, Dattatray G. Deshmukh, Mukund N. Bangal, Anil C. Mali, Vijay J. Medhane
Format: Article
Language:English
Published: Slovenian Chemical Society 2017-06-01
Series:Acta Chimica Slovenica
Subjects:
β3-adrenoceptor agonist
Mirabegron
polymorphism
polymorphic transformation
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/3293

Internet

https://journals.matheo.si/index.php/ACSi/article/view/3293

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