Role of actin filaments and cis binding in cadherin clustering and patterning.

Cadherins build up clusters to maintain intercellular contact through trans and cis (lateral) bindings. Meanwhile, interactions between cadherin and the actin cytoskeleton through cadherin/F-actin linkers can affect cadherin dynamics by corralling and tethering cadherin molecules locally. Despite ma...

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Bibliographic Details
Main Authors: Qilin Yu, Taeyoon Kim, Vijay Rajagopal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010257