TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Abstract Viruses, as opportunistic intracellular parasites, hijack the cellular machinery of host cells to support their survival and propagation. Numerous viral proteins are subjected to host-mediated post-translational modifications. Here, we demonstrate that the SARS-CoV-2 nucleocapsid protein (S...

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Bibliographic Details
Main Authors: Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44502-6

Internet

https://doi.org/10.1038/s41467-023-44502-6

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