From hair to liver: emerging application of hair follicle mesenchymal stem cell transplantation reverses liver cirrhosis by blocking the TGF-β/Smad signaling pathway to inhibit pathological HSC activation

From hair to liver: emerging application of hair follicle mesenchymal stem cell transplantation reverses liver cirrhosis by blocking the TGF-β/Smad signaling pathway to inhibit pathological HSC activation

Liver cirrhosis (LC) involves multiple systems throughout the body, and patients with LC often die of multiple organ failure. However, few drugs are useful to treat LC. Hair follicle mesenchymal stem cells (HF-MSCs) are derived from the dermal papilla and the bulge area of hair follicles and are plu...

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Bibliographic Details
Main Authors: Qi Liu, Chengqian Lv, Yanan Jiang, Kunpeng Luo, Yang Gao, Jingyang Liu, Xu Zhang, Jan Mohammad Omar, Shizhu Jin
Format: Article
Language:English
Published: PeerJ Inc. 2022-02-01
Series:PeerJ
Subjects:
Liver cirrhosis
Hair follicle mesenchymal stem cells
Homing
Differentiation
Hepatic stellate cells
TGF-β/Smad signaling pathway
Online Access:https://peerj.com/articles/12872.pdf

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https://peerj.com/articles/12872.pdf

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