Role of JNK in a Trp53-dependent mouse model of breast cancer.

Role of JNK in a Trp53-dependent mouse model of breast cancer.

The cJun NH2-terminal kinase (JNK) signal transduction pathway has been implicated in mammary carcinogenesis. To test the role of JNK, we examined the effect of ablation of the Jnk1 and Jnk2 genes in a Trp53-dependent model of breast cancer using BALB/c mice. We detected no defects in mammary gland...

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Bibliographic Details
Main Authors: Cristina Cellurale, Claire R Weston, Judith Reilly, David S Garlick, D Joseph Jerry, Hayla K Sluss, Roger J Davis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2930003?pdf=render

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http://europepmc.org/articles/PMC2930003?pdf=render

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