Organotypic Models to Study Human Glioblastoma: Studying the Beast in Its Ecosystem

Summary: Glioblastoma is a very aggressive primary brain tumor in adults, with very low survival rates and no curative treatments. The high failure rate of drug development for this cancer is linked to the high-cost, time-consuming, and inefficient models used to study the disease. Advances in stem...

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Bibliographic Details
Main Authors: David Pamies, Marie-Gabrielle Zurich, Thomas Hartung
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220308257