8-Oxo-2’-deoxyguanosine – biomarker of the oxidative stress

Free radical mechanism of a cell damage is one of the universal non-specific pathogenic pathways in a cause of many diseases, including cancer, neurodegenerative diseases, atherosclerosis and aging. So in nuclear and mitochondrial DNA, guanine hydroxylation to 8-position gives 8­hydroxy­2'­deox...

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Bibliographic Details
Main Authors: T. S. Nevredimova, N. V. Marmiy, D. S. Esipov, O. V. Esipova, V. I. Shvets
Format: Article
Language:Russian
Published: MIREA - Russian Technological University 2014-10-01
Series:Тонкие химические технологии
Subjects:
Online Access:https://www.finechem-mirea.ru/jour/article/view/431