Automated pancreatic islet viability assessment for transplantation using bright-field deep morphological signature

Islets transplanted for type-1 diabetes have their viability reduced by warm ischemia, dimethyloxalylglycine (DMOG; hypoxia model), oxidative stress and cytokine injury. This results in frequent transplant failures and the major burden of patients having to undergo multiple rounds of treatment for i...

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Bibliographic Details
Main Authors: Abbas Habibalahi, Jared M. Campbell, Stacey N. Walters, Saabah B. Mahbub, Ayad G. Anwer, Shane T. Grey, Ewa M. Goldys
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037023000855