Antibacterial spirooxindole alkaloids from Penicillium brefeldianum inhibit dimorphism of pathogenic smut fungi

Antibacterial spirooxindole alkaloids from Penicillium brefeldianum inhibit dimorphism of pathogenic smut fungi

Three new antibacterial spirooxindole alkaloids, spirobrefeldins A–C (1–3), together with four known analogs, spirotryprostatin M (4), spirotryprostatin G (5), 12β-hydroxyverruculogen TR-2 (6), and 12α-hydroxyverruculogen TR-2 (7), were isolated from terrestrial fungus Penicillium brefeldianum. All...

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Bibliographic Details
Main Authors: Huajun Shi, Jinyan Jiang, Hang Zhang, Haimei Jiang, Zijie Su, Dandan Liu, Ligang Jie, Fei He
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Microbiology
Subjects:
Penicillium brefeldianum
spirooxindole diketone piperazine
absolute configuration
antibacterial activities
fungal secondary metabolites
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1046099/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2022.1046099/full

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