Collagen XV Promotes ER Stress-Induced Inflammation through Activating Integrin β1/FAK Signaling Pathway and M1 Macrophage Polarization in Adipose Tissue

Collagen XV Promotes ER Stress-Induced Inflammation through Activating Integrin β1/FAK Signaling Pathway and M1 Macrophage Polarization in Adipose Tissue

Collagen XV (Col XV), a basement membrane (BM) component, is highly expressed in adipose tissue, and studies have found that Col XV is related to extracellular matrix (ECM) remodeling involving in adipose tissue fibrosis and inflammation. Furthermore, the ECM is essential for maintaining normal deve...

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Bibliographic Details
Main Authors: Changxing Li, Yuexia Liu, Yizhou Li, Ruiqing Tai, Zhuwen Sun, Qiong Wu, Yongnian Liu, Chao Sun
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
FAK
Col XV
ERS
inflammation
adipose tissue
Online Access:https://www.mdpi.com/1422-0067/22/18/9997

Internet

https://www.mdpi.com/1422-0067/22/18/9997

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