Integration of single-cell RNA-seq and bulk RNA-seq to construct liver hepatocellular carcinoma stem cell signatures to explore their impact on patient prognosis and treatment.

Integration of single-cell RNA-seq and bulk RNA-seq to construct liver hepatocellular carcinoma stem cell signatures to explore their impact on patient prognosis and treatment.

<h4>Background</h4>Liver hepatocellular carcinoma (LIHC) is a prevalent form of primary liver cancer. Research has demonstrated the contribution of tumor stem cells in facilitating tumor recurrence, metastasis, and treatment resistance. Despite this, there remains a lack of established c...

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Bibliographic Details
Main Authors: Lixia Liu, Meng Zhang, Naipeng Cui, Wenwen Liu, Guixin Di, Yanan Wang, Xin Xi, Hao Li, Zhou Shen, Miaomiao Gu, Zichao Wang, Shan Jiang, Bin Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0298004&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0298004&type=printable

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