Dendrobium alkaloids decrease Aβ by regulating α- and β-secretases in hippocampal neurons of SD rats

Background Alzheimer’s disease (AD) is the primary cause of dementia in the elderly. The imbalance between production and clearance of amyloid β (Aβ) is a very early, often initiating factor in AD. Dendrobium nobile Lindl. alkaloids (DNLA) extracted from a Chinese medicinal herb, which have been sho...

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Bibliographic Details
Main Authors: Juan Huang, Nanqu Huang, Minghui Zhang, Jing Nie, Yunyan Xu, Qin Wu, Jingshan Shi
Format: Article
Language:English
Published: PeerJ Inc. 2019-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/7627.pdf