Integrative binding sites within intracellular termini of TRPV1 receptor.

TRPV1 is a nonselective cation channel that integrates wide range of painful stimuli. It has been shown that its activity could be modulated by intracellular ligands PIP2 or calmodulin (CaM). The detailed localization and description of PIP2 interaction sites remain unclear. Here, we used synthesize...

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Bibliographic Details
Main Authors: Lenka Grycova, Blanka Holendova, Ladislav Bumba, Jan Bily, Michaela Jirku, Zdenek Lansky, Jan Teisinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3485206?pdf=render