Immunophenotypic Alterations in Adult Patients with Steroid-Dependent and Frequently Relapsing Nephrotic Syndrome

Immunophenotypic Alterations in Adult Patients with Steroid-Dependent and Frequently Relapsing Nephrotic Syndrome

Immune dysregulation plays a key role in the pathogenesis of steroid-dependent/frequently relapsing nephrotic syndrome (SDNS/FRNS). However, in contrast with evidence from the pediatric series, no major B- or T-cell alterations have been described for adults. In these patients, treatment with rituxi...

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Bibliographic Details
Main Authors: Federica Casiraghi, Marta Todeschini, Manuel Alfredo Podestà, Marilena Mister, Barbara Ruggiero, Matias Trillini, Camillo Carrara, Olimpia Diadei, Alessandro Villa, Ariela Benigni, Giuseppe Remuzzi
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
nephrotic syndrome
steroid-dependent nephrotic syndrome
steroid-resistant nephrotic syndrome
B cells
regulatory T cells
rituximab
Online Access:https://www.mdpi.com/1422-0067/24/9/7687

Internet

https://www.mdpi.com/1422-0067/24/9/7687

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