Bioartificial pulsatile cuffs fabricated from human induced pluripotent stem cell-derived cardiomyocytes using a pre-vascularization technique

Abstract There is great interest in the development of techniques to bioengineer pulsatile myocardial tissue as a next-generation regenerative therapy for severe heart failure. However, creation of thick myocardial grafts for regenerative medicine requires the incorporation of blood vessels. In this...

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Bibliographic Details
Main Authors: Yuki Endo, Jun Homma, Hidekazu Sekine, Katsuhisa Matsuura, Tatsuya Shimizu, Hiroshi Niinami
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-022-00218-7