Multifaceted Regulations of the Serotonin Transporter: Impact on Antidepressant Response

Multifaceted Regulations of the Serotonin Transporter: Impact on Antidepressant Response

Serotonin transporter, SERT (SLC64A for solute carrier family 6, member A4), is a twelve transmembrane domain (TMDs) protein that assumes the uptake of serotonin (5-HT) through dissipation of the Na+ gradient established by the electrogenic pump Na/K ATPase. Abnormalities in 5-HT level and signaling...

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Bibliographic Details
Main Authors: Anne Baudry, Mathea Pietri, Jean-Marie Launay, Odile Kellermann, Benoit Schneider
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Neuroscience
Subjects:
SERT
SSRIs
microRNAs
trafficking
phosphorylation
Na/K ATPase
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00091/full

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https://www.frontiersin.org/article/10.3389/fnins.2019.00091/full

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