Epigenetic Alterations in Cryopreserved Human Spermatozoa: Suspected Potential Functional Defects

Epigenetic Alterations in Cryopreserved Human Spermatozoa: Suspected Potential Functional Defects

Background: Gene set enrichment analysis (GSEA) was conducted on raw data, and alternative splicing (AS) events were found after mRNA sequencing of human spermatozoa. In this study, we aimed to compare unknown micro-epigenetics alternations in fresh and cryopreserved spermatozoa to evaluate the effe...

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Bibliographic Details
Main Authors: Wanxue Wang, Plamen Todorov, Cheng Pei, Mengying Wang, Evgenia Isachenko, Gohar Rahimi, Peter Mallmann, Vladimir Isachenko
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cells
Subjects:
assisted reproductive technology
cryopreservation
spermatozoa
alternative splicing
exon skipping
Online Access:https://www.mdpi.com/2073-4409/11/13/2110

Internet

https://www.mdpi.com/2073-4409/11/13/2110

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