Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factors

Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factors

<p>Abstract</p> <p>Background</p> <p>Alpha-Synuclein (α-syn), a 140 amino acid protein associated with presynaptic membranes in brain, is a major constituent of Lewy bodies in Parkinson's disease (PD). Three missense mutations (A30P, A53T and E46K) in the α-syn gen...

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Bibliografische gegevens
Hoofdauteurs: Figeys Daniel, Hou Weimin, Marsilio Diana, Whitehead Shawn N, Visanji Naomi P, Wislet-Gendebien Sabine, Fraser Paul E, Bennett Steffany AL, Tandon Anurag
Formaat: Artikel
Taal:English
Gepubliceerd in: BMC 2008-09-01
Reeks:BMC Neuroscience
Online toegang:http://www.biomedcentral.com/1471-2202/9/92

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http://www.biomedcentral.com/1471-2202/9/92

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