IP3R-mediated Ca2+ signaling controls B cell proliferation through metabolic reprogramming

IP3R-mediated Ca2+ signaling controls B cell proliferation through metabolic reprogramming

Summary: Emerging evidence shows that metabolic regulation may be a critical mechanism in B cell activation and function. As targets of several most widely used immunosuppressants, Ca2+ signaling and calcineurin may play an important role in regulating B cell metabolism. Here, we demonstrate that IP...

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Bibliographic Details
Main Authors: Huayuan Tang, Yali Li, Shijia Wang, Jing Ji, Xiangbin Zhu, Yutong Bao, Can Huang, Ye Luo, Lei Huang, Yan Gao, Chaoliang Wei, Jie Liu, Xi Fang, Lu Sun, Kunfu Ouyang
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:iScience
Subjects:
Immunology
Immune response
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222004795

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http://www.sciencedirect.com/science/article/pii/S2589004222004795

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