p53 regulates expression of nuclear envelope components in cancer cells

Abstract Nuclear organisation and architecture are essential for the maintenance of genomic integrity as well as for the epigenetic regulations and gene expression. Disruption of lamin B1, major structural and functional member of the nuclear lamina, is observed in human laminopathies and in sporadi...

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Bibliographic Details
Main Authors: Emanuele Panatta, Alessio Butera, Ivana Celardo, Marcel Leist, Gerry Melino, Ivano Amelio
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Biology Direct
Online Access:https://doi.org/10.1186/s13062-022-00349-3