ChIPulate: A comprehensive ChIP-seq simulation pipeline.

ChIP-seq (Chromatin Immunoprecipitation followed by sequencing) is a high-throughput technique to identify genomic regions that are bound in vivo by a particular protein, e.g., a transcription factor (TF). Biological factors, such as chromatin state, indirect and cooperative binding, as well as expe...

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Bibliographic Details
Main Authors: Vishaka Datta, Sridhar Hannenhalli, Rahul Siddharthan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006921