Acute effects of empagliflozin on open-loop baroreflex function and urinary glucose excretion in rats with chronic myocardial infarction

Acute effects of empagliflozin on open-loop baroreflex function and urinary glucose excretion in rats with chronic myocardial infarction

Abstract Sodium–glucose cotransporter 2 (SGLT2) inhibitors have exerted cardioprotective effects in clinical trials, but underlying mechanisms are not fully understood. As mitigating sympathetic overactivity is of major clinical concern in the mechanisms of heart failure treatments, we examined the...

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Bibliographic Details
Main Authors: Toru Kawada, Meihua Li, Akitsugu Nishiura, Yuki Yoshida, Shohei Yokota, Hiroki Matsushita, Masafumi Fukumitsu, Kazunori Uemura, Joe Alexander, Keita Saku
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Physiological Sciences
Subjects:
Sodium–glucose cotransporter 2
Sympathetic nerve activity
Arterial pressure
Urine flow
Equilibrium diagram
Online Access:https://doi.org/10.1186/s12576-023-00877-1

Internet

https://doi.org/10.1186/s12576-023-00877-1

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