Functionalized 3-hydroxy-3-aminoquinoline-oxindole hybrids as promising dual-function anti-plasmodials

Malaria parasites continue to pose a concern. Drug resistance underlines the need for new structural cores that, when combined with existing antimalarial frameworks, can partially re-sensitize drug-resistant parasites to available antimalarial drugs, such as chloroquine (CQ). Herein, we used “covale...

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Bibliographic Details
Main Authors: Bharvi Sharma, Jenny Legac, Nosipho Cele, Paul Awolade, Philip J. Rosenthal, Parvesh Singh, Vipan Kumar
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:European Journal of Medicinal Chemistry Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772417422000243