Epstein-Barr virus infectious particles initiate B cell transformation and modulate cytokine response
ABSTRACT The Epstein-Barr virus (EBV) efficiently transforms primary B cells. Here, we show that this process starts immediately after cellular exposure to infectious viral particles. Virus binding to B cells led to the activation of intracytoplasmic tyrosine kinases and STAT3. Tegument proteins wit...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2023-10-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mbio.01784-23 |