Association of aldosterone synthase polymorphism (CYP11B2 -344T>C) and genetic ancestry with atrial fibrillation and serum aldosterone in African Americans with heart failure.

Association of aldosterone synthase polymorphism (CYP11B2 -344T>C) and genetic ancestry with atrial fibrillation and serum aldosterone in African Americans with heart failure.

The objective of this study was to examine the extent to which aldosterone synthase genotype (CYP11B2) and genetic ancestry correlate with atrial fibrillation (AF) and serum aldosterone in African Americans with heart failure. Clinical data, echocardiographic measurements, and a genetic sample for d...

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Bibliographic Details
Main Authors: Adam Bress, Jin Han, Shitalben R Patel, Ankit A Desai, Ibrahim Mansour, Vicki Groo, Kristin Progar, Ebony Shah, Thomas D Stamos, Coady Wing, Joe G N Garcia, Rick Kittles, Larisa H Cavallari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3728110?pdf=render

Internet

http://europepmc.org/articles/PMC3728110?pdf=render

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