Booster dose of mRNA vaccine augments waning T cell and antibody responses against SARS-CoV-2

Booster dose of mRNA vaccine augments waning T cell and antibody responses against SARS-CoV-2

A gradual decay in humoral and cellular immune responses over time upon SAR1S-CoV-2 vaccination may cause a lack of protective immunity. We conducted a longitudinal analysis of antibodies, T cells, and monocytes in 25 participants vaccinated with mRNA or ChAdOx1-S up to 12 weeks after the 3rd (boost...

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Bibliographic Details
Main Authors: Feyza Gül Özbay Kurt, Alisa Lepper, Catharina Gerhards, Mathis Roemer, Samantha Lasser, Ihor Arkhypov, Rebekka Bitsch, Peter Bugert, Peter Altevogt, Cécile Gouttefangeas, Michael Neumaier, Jochen Utikal, Viktor Umansky
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
mRNA vaccine
vector vaccine
booster dose
T cell response
antibodies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1012526/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1012526/full

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