Blindness caused by deficiency in AE3 chloride/bicarbonate exchanger.

Blindness caused by deficiency in AE3 chloride/bicarbonate exchanger.

Vision is initiated by phototransduction in the outer retina by photoreceptors, whose high metabolic rate generates large CO2 loads. Inner retina cells then process the visual signal and CO2. The anion exchanger 3 gene (AE3/Slc4a3) encodes full-length AE3 (AE3fl) and cardiac AE3 (AE3c) isoforms, cat...

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Bibliographic Details
Main Authors: Bernardo V Alvarez, Gregory S Gilmour, Silvina C Mema, Brent T Martin, Gary E Shull, Joseph R Casey, Yves Sauvé
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1950688?pdf=render

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http://europepmc.org/articles/PMC1950688?pdf=render

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