Pharmacodynamics of zoliflodacin plus doxycycline combination therapy against Neisseria gonorrhoeae in a gonococcal hollow-fiber infection model

Pharmacodynamics of zoliflodacin plus doxycycline combination therapy against Neisseria gonorrhoeae in a gonococcal hollow-fiber infection model

Antimicrobial resistance in the sexually transmitted bacterium Neisseria gonorrhoeae is compromising the management and control of gonorrhea globally. Optimized use and enhanced stewardship of current antimicrobials and development of novel antimicrobials are imperative. The first in class zolifloda...

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Bibliographic Details
Main Authors: Susanne Jacobsson, Daniel Golparian, Joakim Oxelbark, Fabian Y. S. Kong, Renata Maria Augusto Da Costa, Francois Franceschi, David Brown, Arnold Louie, George Drusano, Magnus Unemo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Pharmacology
Subjects:
Neisseria gonorrhoeae
hollow-fiber infection model
zoliflodacin
doxycycline
pharmacodynamics
antimicrobial treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1291885/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1291885/full

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