Data mining and safety analysis of BTK inhibitors: A pharmacovigilance investigation based on the FAERS database

Objective: The introduction of Bruton’s tyrosine kinase (BTK) inhibitors was a milestone in the treatment of B-cell malignancies in recent years owing to its desired efficacy against chronic lymphocytic leukaemia and small cell lymphocytic lymphoma. However, safety issues have hindered its applicati...

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Bibliographic Details
Main Authors: Qing Wan, Qiang Li, Xin Lai, Tiantian Xu, Jinfang Hu, Hongwei Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.995522/full