Cooperative interactions enable singular olfactory receptor expression in mouse olfactory neurons

Cooperative interactions enable singular olfactory receptor expression in mouse olfactory neurons

The monogenic and monoallelic expression of only one out of >1000 mouse olfactory receptor (ORs) genes requires the formation of large heterochromatic chromatin domains that sequester the OR gene clusters. Within these domains, intergenic transcriptional enhancers evade heterochromatic silenc...

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Bibliographic Details
Main Authors: Kevin Monahan, Ira Schieren, Jonah Cheung, Alice Mumbey-Wafula, Edwin S Monuki, Stavros Lomvardas
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
chromatin
transcription factors
enhancers
olfactory receptors
promoters
Online Access:https://elifesciences.org/articles/28620

Internet

https://elifesciences.org/articles/28620

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