Synthesis, molecular modelling and docking studies of new thieno[2,3-b:4,5-b′] dipyridine compounds as antimicrobial agents

Synthesis, molecular modelling and docking studies of new thieno[2,3-b:4,5-b′] dipyridine compounds as antimicrobial agents

A series of substituted thieno[2,3-b:4,5-b′]dipyridine compounds were synthesized based on the reactions of 2-acetyl-3-aminothieno[2,3-b]pyridine derivative 1 with 1,3-bifunctional reagents (malononitrile, cyanoacetamide, acetylacetone, ethyl acetoacetate) and/or DMF-DMA. The frontier molecular orbi...

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Bibliographic Details
Main Authors: Noof A. Alenazi, Ahmad Fawzi Qarah, Mansoor Alsahag, Haifa Alharbi, Abrar Bayazeed, Salhah D. Al-Qahtani, Nashwa M. El-Metwaly
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Arabian Journal of Chemistry
Subjects:
Thieno-dipyridine
DMF-DMA
DFT/B3LYP
S. aureus
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223003015

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http://www.sciencedirect.com/science/article/pii/S1878535223003015

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