Sphingolipid metabolism in T cell responses after allogeneic hematopoietic cell transplantation

Sphingolipid metabolism in T cell responses after allogeneic hematopoietic cell transplantation

Allogeneic hematopoietic cell transplantation (allo-HCT) is an effective immunotherapy against hematopoietic malignancies. The infused donor lymphocytes attack malignant cells and normal tissues, termed a graft-verse-leukemia (GVL) effect and graft-verse-host (GVH) response or disease (GVHD), respec...

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Bibliographic Details
Main Authors: Linlu Tian, Besim Ogretmen, Brian Y. Chung, Xue-Zhong Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
sphingolipid metabolism
graft versus host disease
graft versus leukemia response
allogeneic hematopoietic cell transplantation
T cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.904823/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.904823/full

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