Detection of Platelet-Activating Antibodies Associated with Heparin-Induced Thrombocytopenia

Detection of Platelet-Activating Antibodies Associated with Heparin-Induced Thrombocytopenia

Heparin-induced thrombocytopenia (HIT) is a prothrombotic immune drug reaction caused by platelet-activating antibodies that in most instances recognize platelet factor 4 (PF4)/polyanion complexes. Platelet activation assays (i.e., functional assays) are more specific than immunoassays, since they a...

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Bibliographic Details
Main Authors: Brigitte Tardy, Thomas Lecompte, François Mullier, Caroline Vayne, Claire Pouplard
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Journal of Clinical Medicine
Subjects:
heparin-induced thrombocytopenia
diagnosis
functional assays
Online Access:https://www.mdpi.com/2077-0383/9/4/1226

Internet

https://www.mdpi.com/2077-0383/9/4/1226

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