Antiphospholipid antibodies induce proinflammatory and procoagulant pathways in endothelial cells

Antiphospholipid antibodies induce proinflammatory and procoagulant pathways in endothelial cells

Antiphospholipid syndrome (APS) is an autoimmune thrombophilia characterized by recurrent thrombotic events and/or pregnancy morbidity in the presence of antiphospholipid antibodies detected either as anti-cardiolipin, anti-β2 Glycoprotein I (anti-β2GPI) or Lupus anticoagulant (LA). Endothelial dere...

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Bibliographic Details
Main Authors: Markos Patsouras, Eirini Alexopoulou, Spyros Foutadakis, Eirini Tsiki, Panagiota Karagianni, Marios Agelopoulos, Panayiotis G. Vlachoyiannopoulos
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Journal of Translational Autoimmunity
Subjects:
Antiphospholipid syndrome (APS)
Transcriptomics analysis
Computational biology tools
Inflammatory and procoagulant phenotype
Transcriptional regulators
Gene expression programs
Online Access:http://www.sciencedirect.com/science/article/pii/S2589909023000151

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http://www.sciencedirect.com/science/article/pii/S2589909023000151

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